info@cytospector.com
Cytospector
  • Home
  • Expertise
  • High-content assays
    • Standardized phenotypic assay
    • Alzheimer´s disease assay
    • Schizophrenia assay
  • Assay development
  • About us
  • Contact
  • Home
  • Expertise
  • High-content assays
    • Standardized phenotypic assay
    • Alzheimer´s disease assay
    • Schizophrenia assay
  • Assay development
  • About us
  • Contact

Rodentneuron

humanipscneuron

Rodent primary neurons and human iPS cell-derived neurons

Cytospector only uses rodent (mouse and rat) primary neurons and human induced pluripotent stem (iPS) cell-derived neurons for its high-content assays. In contrast to neuroblastoma-derived cell lines, these real neurons accurately recapitulate in vivo neurodevelopment and allow quantitative assessment of neuronal network formation and synapse function.

Detailed analysis of synaptic phenotypes

Cytospector has a particular strong expertise in analyzing neuronal morphology, synapse formation, and synaptic transmission. Synaptic pathologies are implicated in many neurological and psychiatric diseases, making our assays highly relevant for research and drug development in this area.

  • synapseswithtracing
  • synapseswithouttracing

Arrayscan

Opera

High-content microscopy

Cytospector uses ThermoScientific ArrayScan HCS Reader and PerkinElmer Opera LX high-content microscopy systems for analysis of neuronal survival, dendrite and synapse morphology, and neuronal connectivity. We perform large-scale, highly sensitive and reproducible in vitro screens, assessing more than 40 neuronal phenotypic parameters that are relevant for neurological and psychiatric disease.

High-content analysis of
synaptic transmission

Cytospector analyzes synaptic transmission by patch clamp physiology on isolated single rodent or human neurons (autaptic cultures). Our automated scripts record over 30 physiological parameters that reflect key synaptic properties.

OVERVIEW AUTAPSES

PATCH CLAMPAUTAPSE

CYTOSPECTOR

  • Home
  • Expertise
  • High-content assays
  • Standardized phenotypic assay
  • Alzheimer´s disease assay
  • Assay development
  • About us
  • Contact

CONTACT

Cytospector
PO Box 71033
1008 BA Amsterdam
The Netherlands

info@cytospector.com

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