Cytospector’s experimental set-up allows for large scale, highly sensitive and reproducible enhancer suppressor or compound screens for a range of CNS relevant phenotypes. Our fully automated cell culture integrated with automated imaging analysis has been validated in a number of screens for neurodegenerative diseases as well as neurotoxicity.
- Rodent primary neurons and human iPS cell-derived neurons
- Detailed analysis of synaptic phenotypes
- High-content microscopy
- High-content analysis of synaptic transmission
Neuron-based high-content assays for compound and genetic screens Using primary rodent neurons and human iPS cell-derived neurons, Cytospector provides high-content, high-throughput cellular screens for a variety of cellular and synaptic phenotypes that are relevant for neurological and psychiatric diseases. Cytospector offers the following assays:
- Standardized phenotypic assay for neuronal and synaptic morphology and function
- Alzheimer’s disease assay
- Schizophrenia assay
On demand, Cytospector develops neuron-based high-content assays for compound screens and screens for therapeutic targets in the field of neurological and psychiatric disease.
Combination of advanced neuronal cell models, standardized analysis of a large number of relevant neuronal and synaptic phenotypes, and our long-standing expertise with high-content screening ensures optimal assay development.
Contact us with any questions or requests for assay development.Contact